MilliporeSigma

TNNI3

troponin I type 3 (cardiac)

Synonyms:
CMD1FF, CMD2A, CMH7, RCM1, TNNC1, cTnI
Species:
UniProtKB ID:
Gene ID:
  • Human(7137) Summary: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]
  • Mouse(21954) troponin I, cardiac 3
  • Rat(29248) troponin I type 3 (cardiac)
  • Horse(100034065) troponin I type 3 (cardiac)
  • sheep(101121961) troponin I type 3 (cardiac)
  • domestic guinea pig(100718375) troponin I type 3 (cardiac)
  • naked mole-rat(101711288) troponin I type 3 (cardiac)
  • chicken(396428) troponin I type 3 (cardiac)
  • dog(403566) troponin I type 3 (cardiac)
  • domestic cat(493744) troponin I type 3 (cardiac)

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ELISA

Product Number
Description
Species
Human TNNI3 / Troponin I, Cardiac Muscle ELISA Kit, ,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
Levosimendan, ≥98% (HPLC),
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TNNI3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human, mouse, pig, rat
Application
ELISA
western blot
Anti-TNNI3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-Tnni3, N-Terminal antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-TNNI3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Monoclonal Anti-TNNI3 antibody produced in mouse, clone 1E7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot

Proteins

Product Number
Description
Species
Troponin I from human heart, lyophilized powder,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Tnni3,
Species
mouse
MISSION® esiRNA, targeting human TNNI3,
Species
human