MilliporeSigma

ADORA1

adenosine A1 receptor

Synonyms:
RDC7
Species:
UniProtKB ID:
Gene ID:
  • Human(134) Summary: The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11539) adenosine A1 receptor
  • Rat(29290) adenosine A1 receptor
  • chicken(374212) adenosine A1 receptor
  • sheep(101109816) adenosine A1 receptor
  • cow(282133) adenosine A1 receptor
  • domestic guinea pig(100135472) adenosine A1 receptor
  • naked mole-rat(101704638) adenosine A1 receptor
  • Zebrafish(100150997) adenosine A1 receptor
  • dog(403961) adenosine A1 receptor
  • domestic cat(101100536) adenosine A1 receptor

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Small Molecule - Agonist

Product Number
Description
Species
(−)-N6-(2-Phenylisopropyl)adenosine, solid,
Species
human
Formycin A, from Streptomyces kaniharaensis, ≥98% (HPLC),
Species
human
2-Phenylaminoadenosine, >97%, solid,
Species
human, rat
AB-MECA, solid,
Species
human, rat
Adenosine, ,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Tubercidin, from Streptomyces tubercidicus, ~95%,
Species
rat
8-Cyclopentyl-1,3-dimethylxanthine, ≥98% (HPLC), powder,
Species
human
Cordycepin, from Cordyceps militaris,
Species
rat
3-Methylxanthine, 98%,
Species
rat
9-Methyladenine, 97%,
Species
rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ADORA1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, rat
Application
ELISA
western blot
Anti-ADORA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-ADORA1 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti-Adenosine A1 Receptor Antibody, Chemicon®, from rabbit,
Species Reactivity
guinea pig, human, pig, rat, sheep
Application
ELISA
immunocytochemistry

immunohistochemistry

western blot
Anti-A1 Adenosine Receptor antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, human, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

Product Number
Description
Species
Nitrendipine, >95%, powder,
Species
human, rat
Caffeine, anhydrous, 99%, FCC, FG,
Species
mouse, human, rat
Caffeine, anhydrous, tested according to Ph. Eur.,
Species
mouse, human, rat
Caffeine, BioXtra,
Species
mouse, human, rat
Caffeine, Sigma Reference Standard, vial of 250 mg,
Species
mouse, human, rat

Small Molecule - Inhibitor

Product Number
Description
Species
8-(3-Chlorostyryl)caffeine, ≥98% (HPLC), solid,
Species
human, rat, mouse
Dilazep dihydrochloride, powder,
Species
human
EHNA hydrochloride, ≥98% (HPLC),
Species
human
Galangin, autophagy inducing flavonoid,
Species
human, rat
5′-Deoxy-5′-(methylthio)adenosine, ,
Species
human, rat, mouse

Small Molecule - Ligand

Product Number
Description
Species
2-Chloro-2′-deoxyadenosine, antileukemic,
Species
rat, human
1,7-Dimethylxanthine, ~98%, solid,
Species
rat, human
Chloro-IB-MECA, solid, ≥98% (HPLC),
Species
human, rat
Adenosine, ≥99%,
Species
human, rat
Theophylline, anhydrous, ≥99%, powder,
Species
mouse, human, rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Adora1,
Species
mouse
MISSION® esiRNA, targeting human ADORA1,
Species
human