APOE
apolipoprotein E
AD2, LDLCQ5, LPG
Human APOE (348), Mouse Apoe (11816), Rat Apoe (25728), naked mole-rat Apoe (101717206), domestic guinea pig Apoe (100731633), cow APOE (281004), Domestic Rabbit APOE (100009337), dog APOE (476438), domestic cat APOE (101086769)
- Human(348) Summary: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008]
- Mouse(11816) apolipoprotein E
- Rat(25728) apolipoprotein E
- naked mole-rat(101717206) apolipoprotein E
- domestic guinea pig(100731633) apolipoprotein E
- cow(281004) apolipoprotein E
- Domestic Rabbit(100009337) apolipoprotein E
- dog(476438) apolipoprotein E
- domestic cat(101086769) apolipoprotein E
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ELISA
Antibodies
Anti-ApoE Antibody, clone 3N14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
human, monkey
affinity binding assay
flow cytometry
immunocytochemistry
flow cytometry
immunocytochemistry
Anti-APOE antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
human
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-APOE (N-terminal) antibody produced in rabbit, affinity isolated antibody,
human, mouse, rat, zebrafish
immunohistochemistry
western blot
western blot
Anti-ApoE4 Fragment nApoECF Antibody (Asp172), from rabbit, purified by affinity chromatography,
bovine, human
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Apolipoprotein E4 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE and HPLC), lyophilized powder,
human