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APOE

apolipoprotein E

Synonyms:
AD2, LDLCQ5, LPG
Species:
UniProtKB ID:
Gene ID:
  • Human(348) Summary: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008]
  • Mouse(11816) apolipoprotein E
  • Rat(25728) apolipoprotein E
  • naked mole-rat(101717206) apolipoprotein E
  • domestic guinea pig(100731633) apolipoprotein E
  • cow(281004) apolipoprotein E
  • Domestic Rabbit(100009337) apolipoprotein E
  • dog(476438) apolipoprotein E
  • domestic cat(101086769) apolipoprotein E

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ELISA

Product Number
Description
Species
Human APOE / Apolipoprotein E ELISA Kit, ,
Species
human
Human APOE / Apolipoprotein E 4 ELISA Kit, ,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ApoE Antibody, clone 3N14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey
Application
affinity binding assay
flow cytometry

immunocytochemistry
Anti-APOE antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-Apolipoprotein E Mouse mAb (E6D7), liquid, clone E6D7, Calbiochem®,
Species Reactivity
human
Application
Anti-APOE (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat, zebrafish
Application
immunohistochemistry
western blot
Anti-ApoE4 Fragment nApoECF Antibody (Asp172), from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, human
Application
immunofluorescence
immunohistochemistry

western blot

Proteins

Product Number
Description
Species
Apolipoprotein E from human plasma, ≥95% (SDS-PAGE),
Species
human
ApoE2 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE), ≥90% (HPLC),
Species
human
Apolipoprotein E4 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE and HPLC), lyophilized powder,
Species
human
Lipoprotein, high density from human plasma, ≥95% (SDS-PAGE), solution,
Species
human
Lipoprotein, low density from human plasma, ≥95% (SDS-PAGE), solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Apoe,
Species
mouse