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ATP7B

ATPase, Cu++ transporting, beta polypeptide

Synonyms:
PWD, WC1, WD, WND
Species:
UniProtKB ID:
Gene ID:
  • Human(540) Summary: This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). [provided by RefSeq, Jul 2008]
  • Mouse(11979) ATPase, Cu++ transporting, beta polypeptide
  • Rat(24218) ATPase, Cu++ transporting, beta polypeptide
  • Zebrafish(556499) ATPase, Cu++ transporting, beta polypeptide (Wilson disease)
  • sheep(443046) ATPase, Cu++ transporting, beta polypeptide
  • chicken(418879) ATPase, Cu++ transporting, beta polypeptide
  • cow(518075) ATPase, Cu++ transporting, beta polypeptide
  • domestic guinea pig(100723125) ATPase, Cu++ transporting, beta polypeptide
  • Domestic Rabbit(100344865) ATPase, Cu++ transporting, beta polypeptide
  • domestic cat(101091495) ATPase, Cu++ transporting, beta polypeptide
  • dog(476903) ATPase, Cu++ transporting, beta polypeptide
  • naked mole-rat(101712944) ATPase, Cu++ transporting, beta polypeptide
  • Horse(100052751) ATPase, Cu++ transporting, beta polypeptide

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-Copper Transporting Atpase 2 - Rpe antibody produced in mouse, clone S62-29, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Monoclonal Anti-Copper Transporting Atpase 2 - Atto 390 antibody produced in mouse, clone S62-29, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Monoclonal Anti-Copper Transporting Atpase 2 - Fitc antibody produced in mouse, clone S62-29, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Monoclonal Anti-Copper Transporting Atpase 2 - Percp antibody produced in mouse, clone S62-29, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-ATP7B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ATP7B,
Species
human
MISSION® esiRNA, targeting mouse Atp7b,
Species
mouse