MilliporeSigma

CHRNA5

cholinergic receptor, nicotinic, alpha 5 (neuronal)

Synonyms:
LNCR2
Species:
UniProtKB ID:
Gene ID:
  • Human(1138) Summary: The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).[provided by RefSeq, Jun 2010]
  • Mouse(110835) cholinergic receptor, nicotinic, alpha polypeptide 5
  • Rat(25102) cholinergic receptor, nicotinic, alpha 5 (neuronal)
  • cow(282177) cholinergic receptor, nicotinic, alpha 5
  • chicken(386577) cholinergic receptor, nicotinic, alpha 5 (neuronal)
  • Domestic Rabbit(100342408) cholinergic receptor, nicotinic, alpha 5 (neuronal)
  • sheep(101115407) cholinergic receptor, nicotinic, alpha 5 (neuronal)
  • naked mole-rat(101714878) cholinergic receptor, nicotinic, alpha 5 (neuronal)
  • Zebrafish(550584) cholinergic receptor, nicotinic, alpha 5
  • domestic cat(101090440) cholinergic receptor, nicotinic, alpha 5 (neuronal)
  • dog(482112) cholinergic receptor, nicotinic, alpha 5 (neuronal)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Product Number
Description
Species
Decamethonium bromide, crystalline,
Species
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Species
human, rat

Small Molecule - Antagonist

Product Number
Description
Species
Mecamylamine hydrochloride, ,
Species
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Species
human, rat
Kynurenic acid, ≥98%,
Species
rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CHRNA5 antibody produced in mouse, clone 7D3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-CHRNA5 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, horse, human, mouse, pig, rabbit, rat
Application
western blot
Anti-CHRNA5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-CHRNA5 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-Nicotinic Acetylcholine Receptor (α1, α3, α5 Subunits) antibody produced in rat, clone mAb 35, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
chicken, eel, human
Application
immunohistochemistry

Small Molecule - Blocker

Product Number
Description
Species
Tetraethylammonium chloride, ≥98% (titration),
Species
human
Hexamethonium chloride, solid (hygroscopic),
Species
human
Hexamethonium bromide, ,
Species
human
Kynurenic acid, ≥98%,
Species
rat, human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CHRNA5, RP11-650L12.2,
Species
human
MISSION® esiRNA, targeting mouse Chrna5,
Species
mouse