MilliporeSigma

COL1A1

collagen, type I, alpha 1

Synonyms:
OI4
Species:
UniProtKB ID:
Gene ID:
  • Human(1277) Summary: This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
  • Mouse(12842) collagen, type I, alpha 1
  • Rat(29393) collagen, type I, alpha 1
  • domestic guinea pig(100733209) collagen, type I, alpha 1
  • chicken(395532) collagen, type I, alpha 1
  • domestic cat(101092216) collagen, type I, alpha 1
  • dog(403651) collagen, type I, alpha 1
  • sheep(443483) collagen, type I, alpha 1
  • Goat(100860828) collagen, type I, alpha 1
  • cow(282187) collagen, type I, alpha 1
  • Horse(100033877) collagen, type I, alpha 1
  • Domestic Rabbit(100008952) collagen, type I, alpha 1
  • naked mole-rat(101703193) collagen, type I, alpha 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-COL1A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-COL1A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Monoclonal Anti-COL1A1 antibody produced in mouse, clone 3G3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry

western blot
Anti-Telo-Collagen Type I, A1/COL1A1, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, sheep
Application
flow cytometry
immunohistochemistry

western blot
Milli-Mark® Anti-Collagen Type I-FITC Antibody, clone 5D8-G9, clone 5D8-G9, Milli-Mark®, from mouse,
Species Reactivity
human
Application
flow cytometry

Proteins

Product Number
Description
Species
Collagen from rat tail, Bornstein and Traub Type I, powder, BioReagent, suitable for cell culture,
Species
rat
Collagen, Type I solution from rat tail, BioReagent, suitable for cell culture, sterile-filtered,
Species
rat
Collagen, from rat tail tendon,
Species
rat
Rat Tail Collagen Coating Solution (20 ML), 50 μg/mL, solution, BioReagent, suitable for cell culture,
Species
rat
Human Collagen Type I, ,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human COL1A1,
Species
human
MISSION® esiRNA, targeting mouse Col1a1,
Species
mouse