MilliporeSigma

CREB1

cAMP responsive element binding protein 1

Synonyms:
CREB
Species:
UniProtKB ID:
Gene ID:
  • Human(1385) Summary: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(12912) cAMP responsive element binding protein 1
  • Rat(81646) cAMP responsive element binding protein 1
  • chicken(395099) cAMP responsive element binding protein 1
  • dog(607922) cAMP responsive element binding protein 1
  • domestic guinea pig(100727326) cAMP responsive element binding protein 1
  • naked mole-rat(101712503) cAMP responsive element binding protein 1
  • domestic cat(101091299) cAMP responsive element binding protein 1
  • cow(281713) cAMP responsive element binding protein 1
  • Horse(100066388) cAMP responsive element binding protein 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Phospho-CREB1-S133 antibody produced in rabbit, ,
Species Reactivity
human, rat
Application
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Phospho-CREB1-S133 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-CREB-1 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
equine, human, porcine, rat
Application
ChIP
immunocytochemistry

western blot
Anti-NR3B Antibody, Upstate®, from rabbit,
Species Reactivity
mouse, rat
Application
western blot
Anti-phospho-CREB (Ser133) Antibody, Upstate®, from rabbit,
Species Reactivity
hamster, human, mouse, rat
Application
electrophoretic mobility shift assay
immunohistochemistry

immunoprecipitation (IP)

western blot

Proteins

Product Number
Description
Species
CREB1 (1-280), GST tagged from rat, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
rat
CREB Binding Protein (1081-1197) GST tag human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CREB1,
Species
human
MISSION® esiRNA, targeting mouse Creb1,
Species
mouse