MilliporeSigma

GLE1

GLE1 RNA export mediator

Synonyms:
GLE1L, LCCS, LCCS1, hGLE1
Species:
UniProtKB ID:
Gene ID:
  • Human(2733) Summary: This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(74412) GLE1 RNA export mediator (yeast)
  • Rat(362098) GLE1 RNA export mediator
  • sheep(101119123) GLE1 RNA export mediator homolog (yeast)
  • Horse(100066964) GLE1 RNA export mediator homolog (yeast)
  • domestic guinea pig(100732111) GLE1 RNA export mediator
  • naked mole-rat(101722063) GLE1 RNA export mediator homolog (yeast)
  • cow(540982) GLE1 RNA export mediator homolog (yeast)
  • chicken(417212) GLE1 RNA export mediator
  • Zebrafish(445408) GLE1 RNA export mediator homolog (yeast)
  • dog(480704) GLE1 RNA export mediator homolog (yeast)
  • domestic cat(101080492) GLE1 RNA export mediator homolog (yeast)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GLE1 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-GLE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-GLE1L antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-GLE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-GLE1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
horse, human, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GLE1,
Species
human
MISSION® esiRNA, targeting mouse Gle1,
Species
mouse