MilliporeSigma

GPNMB

glycoprotein (transmembrane) nmb

Synonyms:
HGFIN, NMB
Species:
UniProtKB ID:
Gene ID:
  • Human(10457) Summary: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(93695) glycoprotein (transmembrane) nmb
  • Rat(113955) glycoprotein (transmembrane) nmb
  • Zebrafish(563348) glycoprotein (transmembrane) nmb
  • naked mole-rat(101726702) glycoprotein (transmembrane) nmb
  • dog(482355) glycoprotein (transmembrane) nmb
  • domestic guinea pig(100734622) glycoprotein (transmembrane) nmb
  • sheep(101109959) glycoprotein (transmembrane) nmb
  • domestic cat(101090001) glycoprotein (transmembrane) nmb
  • chicken(428431) glycoprotein (transmembrane) nmb
  • cow(509600) glycoprotein (transmembrane) nmb
  • Horse(100067870) glycoprotein (transmembrane) nmb

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ELISA

Product Number
Description
Species
Human GPNMB / Transmembrane Glycoprotein NMB ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human
Mouse Osteoactivin ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-GPNMB antibody produced in mouse, clone 3A5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-GPNMB antibody produced in mouse, clone 1A8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-GPNMB, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, human, mouse, pig, rat
Application
western blot
Anti-GPNMB antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
guinea pig, horse, human, mouse, rat
Application
western blot
Anti-GPNMB, affinity isolated antibody,
Species Reactivity
bovine, horse, human, mouse, rabbit
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GPNMB,
Species
human
MISSION® esiRNA, targeting mouse Gpnmb,
Species
mouse