MilliporeSigma

GPX4

glutathione peroxidase 4

Synonyms:
GPx-4, GSHPx-4, MCSP, PHGPx, snGPx, snPHGPx
Species:
UniProtKB ID:
Gene ID:
  • Human(2879) Summary: Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. [provided by RefSeq, Jul 2008]
  • Mouse(625249) glutathione peroxidase 4
  • Rat(29328) glutathione peroxidase 4
  • domestic guinea pig(100730119) glutathione peroxidase 4
  • naked mole-rat(101708875) glutathione peroxidase 4
  • Thale Cress(819427) glutathione peroxidase 4
  • chicken(374056) glutathione peroxidase 4
  • domestic cat(101095956) glutathione peroxidase 4
  • cow(286809) glutathione peroxidase 4
  • Goat(100860867) glutathione peroxidase 4
  • sheep(101113149) glutathione peroxidase 4

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GPX4 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-GPX4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-GPX4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-GPX4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-GPX4, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GPX4,
Species
human