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HDAC2

histone deacetylase 2

Synonyms:
HD2, RPD3, YAF1
Species:
UniProtKB ID:
Gene ID:
  • Human(3066) Summary: This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
  • Mouse(15182) histone deacetylase 2
  • Rat(84577) histone deacetylase 2
  • chicken(395635) histone deacetylase 2
  • domestic cat(101088165) histone deacetylase 2
  • dog(475035) histone deacetylase 2
  • sheep(101107708) histone deacetylase 2
  • cow(407223) histone deacetylase 2
  • naked mole-rat(101712029) histone deacetylase 2
  • domestic guinea pig(100715675) histone deacetylase 2

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
ChIPAb+ HDAC2 - ChIP Validated Antibody and Primer Set, from mouse,
Species Reactivity
bovine, hamster, human, mouse, rat
Application
ChIP
western blot
Anti-HDAC2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-HDAC2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-HDAC2 (Ab-394) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-phospho-HDAC2 (pSer394) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
SAHA, ≥98% (HPLC),
Species
human
Romidepsin, ≥98% (HPLC),
Species
human
CI−994, ≥98% (HPLC), powder,
Species
human

Proteins

Product Number
Description
Species
HDAC2 FLAG tag human, recombinant, expressed in baculovirus infected insect cells, ≥50% (SDS-PAGE),
Species
human
HDAC2, active, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
HDAC 2 His tag human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Hdac2,
Species
mouse
MISSION® esiRNA, targeting human HDAC2,
Species
human