MilliporeSigma

IKBKB

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta

Synonyms:
IKK-beta, IKK2, IKKB, NFKBIKB
Species:
UniProtKB ID:
Gene ID:
  • Human(3551) Summary: The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene. [provided by RefSeq, Sep 2011]
  • Mouse(16150) inhibitor of kappaB kinase beta
  • Rat(84351) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • Zebrafish(563560) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • cow(281854) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • domestic cat(100142682) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • dog(482839) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • chicken(426792) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • naked mole-rat(101711077) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • domestic guinea pig(100724538) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IKBKB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-IKKβ Antibody, clone 10AG2, clone 10AG2, Upstate®, from mouse,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-IKKβ Antibody, clone 8X6V3, Rabbit Monoclonal, ,
Species Reactivity
mouse, rat
Application
immunofluorescence
Anti-IKK-β antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
ANTI-IKBKB antibody produced in mouse, clone 2F4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Norharmane, crystalline,
Species
human
CDDO Methyl Ester, ≥98% (HPLC),
Species
human

Proteins

Product Number
Description
Species
IKKβ, ,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human IKBKB,
Species
human
MISSION® esiRNA, targeting mouse Ikbkb,
Species
mouse