MilliporeSigma

IRF3

interferon regulatory factor 3

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(3661) Summary: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
  • Mouse(54131) interferon regulatory factor 3
  • Rat(292892) interferon regulatory factor 3
  • domestic guinea pig(100724910) interferon regulatory factor 3
  • sheep(780485) interferon regulatory factor 3
  • cow(516979) interferon regulatory factor 3
  • domestic cat(101095934) interferon regulatory factor 3
  • naked mole-rat(101722762) interferon regulatory factor 3
  • Zebrafish(564854) interferon regulatory factor 3
  • dog(476412) interferon regulatory factor 3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IRF3 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-IRF3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-IRF3 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-phospho-IRF-3 (pSer385) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
western blot
Anti-IRF3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, human, rat, sheep
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human IRF3,
Species
human