MilliporeSigma

ITGAV

integrin, alpha V

Synonyms:
CD51, MSK8, VNRA, VTNR
Species:
UniProtKB ID:
Gene ID:
  • Human(3685) Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]
  • Mouse(16410) integrin alpha V
  • Rat(296456) integrin, alpha V
  • dog(488437) integrin, alpha V
  • naked mole-rat(101717672) integrin, alpha V
  • domestic guinea pig(100728575) integrin, alpha V
  • domestic cat(101085820) integrin, alpha V
  • chicken(396420) integrin, alpha V
  • Zebrafish(100151255) integrin, alpha V
  • Domestic Rabbit(100008956) integrin, alpha V
  • cow(281875) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • sheep(443143) integrin, alpha V
  • Horse(100068706) integrin, alpha V

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Small Molecule - Antagonist

Product Number
Description
Species
Gly-Arg-Gly-Asp-Ser-Pro-Lys, ≥97% (HPLC),
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Integrin αV Antibody, extracellular, clone AV1, azide free, culture supernatant, clone AV1, Chemicon®,
Species Reactivity
human
Application
flow cytometry
western blot
Anti-Integrin αVβ3 Antibody, clone 27.1 (VNR-1), clone 27.1 (VNR-1), Chemicon®, from mouse,
Species Reactivity
human
Application
immunofluorescence
immunoprecipitation (IP)
Anti-Integrin αVβ3 Antibody, clone LM609, biotin conjugated, clone LM609, Chemicon®, from mouse,
Species Reactivity
avian, bovine, canine, chicken, human, monkey, pig, rabbit
Application
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Anti-Integrin αVβ6 Antibody, clone E7P6, azide free, clone E7P6, Chemicon®, from mouse,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry

immunohistochemistry
Anti-Integrin αVβ3 Antibody, clone EM22703 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry

immunofluorescence

immunohistochemistry

Proteins

Product Number
Description
Species
Human Integrin αVβ3, Octyl-β-D-glucopyranoside Formulation, ,
Species
human
Human Integrin αVβ3 Protein, Triton X-100 Formulation, ,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Itgav,
Species
mouse
MISSION® esiRNA, targeting human ITGAV,
Species
human