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KLK3

kallikrein-related peptidase 3

Synonyms:
APS, KLK2A1, PSA, hK3
Species:
UniProtKB ID:
Gene ID:
  • Human(354) Summary: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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ELISA

Product Number
Description
Species
Human PSA-total ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Human KLK3 / Prostate-specific Antigen ELISA Kit, ,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-KLK3 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
proximity ligation assay
western blot
Monoclonal Anti-KLK3 antibody produced in mouse, clone 5A11E9, ascites fluid,
Species Reactivity
human
Application
ELISA
flow cytometry

immunohistochemistry

western blot
PSA (ER-PR8) Mouse Monoclonal Antibody, ,
Species Reactivity
human
Application
immunohistochemistry
Anti-PSA Antibody, clone 1E10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-PSA (10mg) KC, from mouse,
Species Reactivity
human
Application
ELISA
immunodiffusion

Proteins

Product Number
Description
Species
Kallikrein-3 human, recombinant, expressed in human cells, ≥95% (SDS-PAGE),
Species
human
Prostate Specific Antigen from human semen, buffered aqueous solution,
Species
human
Prostate Specific Antigen from human semen, buffered aqueous solution,
Species
human
Prostate Specific Antigen–α1-Antichymotrypsin Complex human, ≥99% (SDS-PAGE), buffered aqueous solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human KLK3,
Species
human