KLK3
kallikrein-related peptidase 3
APS, KLK2A1, PSA, hK3
- Human(354) Summary: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Antibodies
Anti-KLK3 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
human
proximity ligation assay
western blot
western blot
Monoclonal Anti-KLK3 antibody produced in mouse, clone 5A11E9, ascites fluid,
human
ELISA
flow cytometry
immunohistochemistry
western blot
flow cytometry
immunohistochemistry
western blot
Anti-PSA Antibody, clone 1E10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
human
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Proteins
Prostate Specific Antigen–α1-Antichymotrypsin Complex human, ≥99% (SDS-PAGE), buffered aqueous solution,
human