MilliporeSigma

MMP24

matrix metallopeptidase 24 (membrane-inserted)

Synonyms:
MMP-24, MMP25, MT-MMP 5, MT-MMP5, MT5-MMP, MT5MMP, MTMMP5
Species:
UniProtKB ID:
Gene ID:
  • Human(10893) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. [provided by RefSeq, Jul 2008]
  • Mouse(17391) matrix metallopeptidase 24
  • Rat(83513) matrix metallopeptidase 24
  • Horse(100069462) matrix metallopeptidase 24 (membrane-inserted)
  • dog(485849) matrix metallopeptidase 24 (membrane-inserted)
  • domestic cat(101087914) matrix metallopeptidase 24 (membrane-inserted)
  • naked mole-rat(101702877) matrix metallopeptidase 24 (membrane-inserted)
  • Domestic Rabbit(100328896) matrix metallopeptidase 24 (membrane-inserted)
  • chicken(419141) matrix metallopeptidase 24 (membrane-inserted)
  • sheep(101119580) matrix metallopeptidase 24 (membrane-inserted)
  • Zebrafish(571143) matrix metallopeptidase 24
  • cow(536622) matrix metallopeptidase 24 (membrane-inserted)
  • domestic guinea pig(100731826) matrix metallopeptidase 24 (membrane-inserted)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MMP24 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-MMP24 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-MT5-MMP/MMP24 Antibody, ,
Species Reactivity
human, mouse
Application
western blot
Anti-Matrix Metalloproteinase-24, Hinge Region antibody produced in rabbit, ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse
Application
ELISA
flow cytometry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Matrix Metalloproteinase-24, Cytoplasmic antibody produced in rabbit, ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse
Application
ELISA
flow cytometry

immunohistochemistry

immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
CP-101537, ≥98% (HPLC),
Species
human, rat, mouse
CP-471474, ≥98% (HPLC),
Species
human, rat, mouse
Marimastat, ≥98% (HPLC),
Species
human, rat, mouse
PD166793 hydrate, ≥98% (HPLC),
Species
human, rat, mouse

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MMP24,
Species
human
MISSION® esiRNA, targeting mouse Mmp24,
Species
mouse