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NEFH

neurofilament, heavy polypeptide

Synonyms:
NFH
Species:
UniProtKB ID:
Gene ID:
  • Human(4744) Summary: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]
  • Mouse(380684) neurofilament, heavy polypeptide
  • Rat(24587) neurofilament, heavy polypeptide
  • chicken(417020) neurofilament, heavy polypeptide
  • domestic cat(101087272) neurofilament, heavy polypeptide
  • naked mole-rat(101704170) neurofilament, heavy polypeptide
  • domestic guinea pig(100716406) neurofilament, heavy polypeptide
  • sheep(101107472) neurofilament, heavy polypeptide
  • cow(528842) neurofilament, heavy polypeptide
  • dog(442940) neurofilament, heavy polypeptide

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-Neurofilament H, purified produced in mouse, ,
Species Reactivity
Application
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-NEFH antibody produced in mouse, clone 2E8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
PhosphoDetect Anti-Neurofilament H Mouse mAb (SMI-31), liquid, clone SMI-31, Calbiochem®,
Species Reactivity
xenopus, chicken, mammals
Application
Anti-Neurofilament H Antibody, clone 7L2V7, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-NEFH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human NEFH,
Species
human