Skip to Content
MilliporeSigma

PAK1

p21 protein (Cdc42/Rac)-activated kinase 1

Synonyms:
PAKalpha
Species:
UniProtKB ID:
Gene ID:
  • Human(5058) Summary: This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
  • Mouse(18479) p21 protein (Cdc42/Rac)-activated kinase 1
  • Rat(29431) p21 protein (Cdc42/Rac)-activated kinase 1
  • domestic guinea pig(100714662) p21 protein (Cdc42/Rac)-activated kinase 1
  • naked mole-rat(101713465) p21 protein (Cdc42/Rac)-activated kinase 1
  • Zebrafish(373103) p21/Cdc42/Rac1-activated kinase 1
  • chicken(419083) p21 protein (Cdc42/Rac)-activated kinase 1
  • dog(607885) p21 protein (Cdc42/Rac)-activated kinase 1
  • domestic cat(101087171) p21 protein (Cdc42/Rac)-activated kinase 1
  • cow(533729) p21 protein (Cdc42/Rac)-activated kinase 1
  • sheep(101111756) p21 protein (Cdc42/Rac)-activated kinase 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PAK1 antibody produced in mouse, clone 1E11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-phospho-PAK1 (pSer199) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-phospho-PAK1/2/3 (pThr423) antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
western blot
Anti-PAK1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-PAK1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot

Proteins

Product Number
Description
Species
PAK1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Pak1,
Species
mouse
MISSION® esiRNA, targeting human PAK1,
Species
human