MilliporeSigma

PDGFRB

platelet-derived growth factor receptor, beta polypeptide

Synonyms:
CD140B, IBGC4, IMF1, JTK12, PDGFR, PDGFR-1, PDGFR1
Species:
UniProtKB ID:
Gene ID:
  • Human(5159) Summary: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008]
  • Mouse(18596) platelet derived growth factor receptor, beta polypeptide
  • Rat(24629) platelet derived growth factor receptor, beta polypeptide
  • domestic guinea pig(100726506) platelet-derived growth factor receptor, beta polypeptide
  • naked mole-rat(101721151) platelet-derived growth factor receptor, beta polypeptide
  • Zebrafish(559529) platelet-derived growth factor receptor beta
  • chicken(770488) platelet-derived growth factor receptor, beta polypeptide
  • dog(442985) platelet-derived growth factor receptor, beta polypeptide
  • domestic cat(101084600) platelet-derived growth factor receptor, beta polypeptide
  • cow(527165) platelet-derived growth factor receptor, beta polypeptide
  • Domestic Rabbit(100342872) platelet-derived growth factor receptor, beta polypeptide
  • sheep(101122783) platelet-derived growth factor receptor, beta polypeptide

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ELISA

Product Number
Description
Species
Mouse PDGF-BB ELISA, for serum, plasma and cell culture supernatants,
Species
mouse
Phosphotyrosine PDGFRB / Platelet-derived Growth Factor Receptor Beta ELISA Kit, ,
Species
human
Rhesus Macaque PDGF R beta ELISA, for serum, plasma and cell culture supernatants,
Species
Human PDGF R β ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PDGFRB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Monoclonal Anti-CD140b antibody produced in mouse, clone 18A2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Anti-PDGFR β antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-PDGFRβ Antibody, clone 4A56, rabbit monoclonal, culture supernatant, clone 4A56, Upstate®,
Species Reactivity
human, mouse
Application
immunoprecipitation (IP)
western blot
MONOCLONAL ANTI-PDGFR antibody produced in mouse, clone 275CT1, crude ascites, buffered aqueous solution,
Species Reactivity
mouse
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
2-Phenylbenzimidazole, 97%,
Species
human
Imatinib, ,
Species
human
Tyrphostin A9, solid,
Species
mouse, human
SU 5416, ≥98% (HPLC),
Species
human, mouse
Pazopanib, ,
Species
human

Proteins

Product Number
Description
Species
PDGFRb/CD140b human, recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE),
Species
human
PDGFRβ Protein, active, 50 µg, Active, recombinant human PDGF Receptor β, residues 557-end, containing an N-terminal His6-tag, for use in Kinase Assays.,
Species
human
PDGFRb active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
Species
human
PDGFRβ(557-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PDGFRB,
Species
human