MilliporeSigma

PUF60

poly-U binding splicing factor 60KDa

Synonyms:
FIR, RoBPI, SIAHBP1
Species:
UniProtKB ID:
Gene ID:
  • Human(22827) Summary: This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
  • Mouse(67959) poly-U binding splicing factor 60
  • Rat(84401) poly-U binding splicing factor 60
  • domestic guinea pig(100734967) poly-U binding splicing factor 60KDa
  • naked mole-rat(101711469) poly-U binding splicing factor 60KDa
  • cow(512824) poly-U binding splicing factor 60KDa
  • sheep(101112401) poly-U binding splicing factor 60KDa
  • chicken(426402) poly-U binding splicing factor 60KDa
  • domestic cat(101092241) poly-U binding splicing factor 60KDa
  • dog(607245) poly-U binding splicing factor 60KDa

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PUF60 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-PUF60 antibody produced in mouse, clone 1C1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-PUF60 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-PUF60 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PUF60,
Species
human
MISSION® esiRNA, targeting mouse Puf60,
Species
mouse