MilliporeSigma

RPTOR

regulatory associated protein of MTOR, complex 1

Synonyms:
KOG1, Mip1
Species:
UniProtKB ID:
Gene ID:
  • Human(57521) Summary: This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(74370) regulatory associated protein of MTOR, complex 1
  • Rat(287871) regulatory associated protein of MTOR, complex 1
  • domestic guinea pig(100729707) regulatory associated protein of MTOR, complex 1
  • domestic cat(101086862) regulatory associated protein of MTOR, complex 1
  • naked mole-rat(101724257) regulatory associated protein of MTOR, complex 1
  • cow(507056) regulatory associated protein of MTOR, complex 1
  • sheep(101119321) regulatory associated protein of MTOR, complex 1
  • Zebrafish(560455) regulatory associated protein of MTOR, complex 1
  • chicken(428674) regulatory associated protein of MTOR, complex 1
  • dog(608378) regulatory associated protein of MTOR, complex 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Phospho-RPTOR-Ser792 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
western blot
Anti-Raptor Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot
Anti-RPTOR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
ANTI-PHOSPHO-RAPTOR(S863) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
Monoclonal Anti-RPTOR, (C-terminal) antibody produced in mouse, clone 3C2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA

Proteins

Product Number
Description
Species
mTOR/Raptor/MLST8 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥50% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Rptor,
Species
mouse