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MilliporeSigma

SCNN1B

sodium channel, non-voltage-gated 1, beta subunit

Synonyms:
BESC1, ENaCb, ENaCbeta, SCNEB
Species:
Human SCNN1B (6338), Mouse Scnn1b (20277), Rat Scnn1b (24767), chicken SCNN1B (427673), dog SCNN1B (489972), Horse SCNN1B (100069008), domestic cat SCNN1B (101099767), cow SCNN1B (533355), sheep SCNN1B (100170325), Goat SCNN1B (100861026) ...More
UniProtKB ID:
P51168, C5HTZ2, O60891, Q96KG2, Q9UJ32, Q9UMU5
Gene ID:
  • Human(6338) Summary: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome. [provided by RefSeq, Apr 2009]
  • Mouse(20277) sodium channel, nonvoltage-gated 1 beta
  • Rat(24767) sodium channel, nonvoltage-gated 1, beta
  • chicken(427673) sodium channel, non-voltage-gated 1, beta subunit
  • dog(489972) sodium channel, non-voltage-gated 1, beta subunit
  • Horse(100069008) sodium channel, non-voltage-gated 1, beta subunit
  • domestic cat(101099767) sodium channel, non-voltage-gated 1, beta subunit
  • cow(533355) sodium channel, nonvoltage-gated 1, beta
  • sheep(100170325) sodium channel, non-voltage-gated 1, beta subunit
  • Goat(100861026) sodium channel, non-voltage-gated 1, beta subunit
  • Domestic Rabbit(100009564) sodium channel, non-voltage-gated 1, beta subunit
  • domestic guinea pig(100270805) sodium channel, nonvoltage-gated 1 beta
  • naked mole-rat(101717352) sodium channel, non-voltage-gated 1, beta subunit

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Antibodies

Product Number
Description
Species Reactivity
Application
HPA015612
Anti-SCNN1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
SAB5201817
Monoclonal Anti-ENaC beta-Biotin antibody produced in mouse, clone 16E4,
Species Reactivity
mouse
Application
western blot
SAB5201808
Monoclonal Anti-ENaC beta-Atto 488 antibody produced in mouse, clone 16E4,
Species Reactivity
mouse
Application
western blot
SAB5201799
Monoclonal Anti-ENaC beta-Biotin antibody produced in mouse, clone 7B8,
Species Reactivity
mouse
Application
immunohistochemistry
western blot
SAB5201790
Monoclonal Anti-ENaC beta-Atto 488 antibody produced in mouse, clone 7B8,
Species Reactivity
mouse
Application
immunohistochemistry
western blot

Small Molecule - Blocker

Product Number
Description
Species
T4143
Triamterene, ≥99%,
Species
human
Y0000837
Triamterene, European Pharmacopoeia (EP) Reference Standard,
Species
human
1680007
Triamterene, United States Pharmacopeia (USP) Reference Standard,
Species
human
BP340
Triamterene, British Pharmacopoeia (BP) Reference Standard,
Species
human
PHR1722
Triamterene, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
B2417
Benzamil hydrochloride hydrate, ≥98% (HPLC),
Species
mouse, rat, human
P203
Phenamil methanesulfonate salt, solid,
Species
mouse, rat, human
A5585
5-(N-Methyl-N-isobutyl)­amiloride, ≥98% (TLC), powder,
Species
mouse, rat, human
A4562
5-(N,N-Dimethyl)amiloride hydrochloride, ,
Species
rat, mouse, human
A9561
5-(N,N-Hexamethylene)amiloride, ,
Species
rat, human, mouse

esiRNA

Product Number
Description
Species
EHU066451
MISSION® esiRNA, targeting human SCNN1B,
Species
human