MilliporeSigma

SELPLG

selectin P ligand

Synonyms:
CD162, CLA, PSGL-1, PSGL1
Species:
UniProtKB ID:
Gene ID:
  • Human(6404) Summary: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
  • Mouse(20345) selectin, platelet (p-selectin) ligand
  • Rat(363930) selectin P ligand
  • domestic guinea pig(100712957) selectin P ligand
  • Horse(100034025) selectin P ligand
  • chicken(772212) selectin P ligand
  • Zebrafish(100884146) selectin P ligand
  • sheep(101102589) selectin P ligand
  • cow(617434) selectin P ligand
  • domestic cat(101087945) selectin P ligand
  • dog(611673) selectin P ligand
  • naked mole-rat(101713908) selectin P ligand

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ELISA

Product Number
Description
Species
Human PSGL-1 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CD162-APC antibody produced in mouse, clone TC2,
Species Reactivity
Application
flow cytometry
Anti-PSGL-1/CD162 Antibody, clone KPL-1 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-SELPLG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-PSGL-1/CD162 Antibody, clone HECA-452, ,
Species Reactivity
human
Application
flow cytometry
immunohistochemistry

western blot
Anti-P-Selectin Glycoprotein Ligand-1 Antibody, clone KPL-1, clone KPL-1, Chemicon®, from mouse,
Species Reactivity
human
Application
flow cytometry
immunohistochemistry

immunoprecipitation (IP)

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Selplg,
Species
mouse
MISSION® esiRNA, targeting human SELPLG,
Species
human