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SERPINC1

serpin peptidase inhibitor, clade C (antithrombin), member 1

Synonyms:
AT3, AT3D, ATIII, THPH7
Species:
UniProtKB ID:
Gene ID:
  • Human(462) Summary: The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq, Jul 2009]
  • Mouse(11905) serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
  • Rat(304917) serpin peptidase inhibitor, clade C (antithrombin), member 1
  • chicken(424440) serpin peptidase inhibitor, clade C (antithrombin), member 1
  • Zebrafish(321545) serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
  • Horse(100061173) serpin peptidase inhibitor, clade C (antithrombin), member 1
  • domestic cat(101093983) serpin peptidase inhibitor, clade C (antithrombin), member 1
  • dog(480066) serpin peptidase inhibitor, clade C (antithrombin), member 1
  • sheep(443407) serpin peptidase inhibitor, clade C (antithrombin), member 1
  • cow(540261) serpin peptidase inhibitor, clade C (antithrombin), member 1
  • Domestic Rabbit(100355802) serpin peptidase inhibitor, clade C (antithrombin), member 1
  • naked mole-rat(101722222) serpin peptidase inhibitor, clade C (antithrombin), member 1
  • domestic guinea pig(100379601) serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1

Custom & Knockdown Gene Products

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ELISA

Product Number
Description
Species
Human Antithrombin 3 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-SERPINC1 antibody produced in mouse, clone 2B12, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
Anti-SERPINC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-SERPINC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-Antithrombin III antibody produced in rabbit, fractionated antiserum, lyophilized powder,
Species Reactivity
human
Application
ELISA
Anti-SERPINC1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
Antithrombin III from human plasma, lyophilized powder, ≥95% (SDS-PAGE),
Species
human
Antithrombin III from human plasma, ≥95% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Serpinc1,
Species
mouse
MISSION® esiRNA, targeting human SERPINC1,
Species
human