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SGK1

serum/glucocorticoid regulated kinase 1

Synonyms:
SGK
Species:
UniProtKB ID:
Gene ID:
  • Human(6446) Summary: This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
  • Mouse(20393) serum/glucocorticoid regulated kinase 1
  • Rat(29517) serum/glucocorticoid regulated kinase 1
  • chicken(395133) serum/glucocorticoid regulated kinase 1
  • cow(515854) serum/glucocorticoid regulated kinase 1
  • Domestic Rabbit(100008723) serum/glucocorticoid regulated kinase 1
  • domestic cat(101098954) serum/glucocorticoid regulated kinase 1
  • dog(403647) serum/glucocorticoid regulated kinase 1
  • sheep(101107709) serum/glucocorticoid regulated kinase 1
  • Zebrafish(324140) serum/glucocorticoid regulated kinase 1
  • domestic guinea pig(100720058) serum/glucocorticoid regulated kinase 1
  • naked mole-rat(101708117) serum/glucocorticoid regulated kinase 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SGK antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-SGK (pSer78) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-phospho-SGK (pSer422) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-phospho-SGK Antibody, serum, Upstate®,
Species Reactivity
human
Application
western blot
Anti-SGK antibody produced in rabbit, buffered aqueous solution, IgG fraction of antiserum,
Species Reactivity
human
Application
immunofluorescence
microarray

western blot

Proteins

Product Number
Description
Species
SGK1 (60-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
SGK1 (δ1-60, S422D), active human, recombinant, expressed in baculovirus infected Sf9 cells (truncated human sequence (a.a. 1-60 deleted, S422D mutation)-histidine-tagged), buffered aqueous solution,
Species
human
SGK1 (δ1-59, S422D) Protein, active, 6 µg, Active, N-truncated (missing N-terminal 60 amino acids), His-tagged, human SGK1 fusion protein, containing a S422D mutation, for use in Kinase Assays.,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SGK1,
Species
human
MISSION® esiRNA, targeting mouse Sgk1,
Species
mouse