MilliporeSigma

THRA

thyroid hormone receptor, alpha

Synonyms:
AR7, CHNG6, EAR7, ERB-T-1, ERBA, ERBA1, NR1A1, THRA1, THRA2, c-ERBA-1
Species:
UniProtKB ID:
Gene ID:
  • Human(7067) Summary: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(21833) thyroid hormone receptor alpha
  • Rat(81812) thyroid hormone receptor alpha
  • chicken(396251) thyroid hormone receptor, alpha
  • naked mole-rat(101726699) thyroid hormone receptor, alpha
  • domestic guinea pig(100726737) thyroid hormone receptor, alpha
  • sheep(443446) thyroid hormone receptor, alpha
  • Domestic Rabbit(100303772) thyroid hormone receptor, alpha
  • cow(532621) thyroid hormone receptor, alpha
  • domestic cat(101095056) thyroid hormone receptor, alpha
  • dog(403601) thyroid hormone receptor, alpha

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Small Molecule - Agonist

Product Number
Description
Species
Liothyronine sodium, European Pharmacopoeia (EP) Reference Standard,
Species
human
Levothyroxine sodium, United States Pharmacopeia (USP) Reference Standard,
Species
human
3,3′,5-Triiodo-L-thyronine (T3) solution, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
L-Thyroxine (T4) solution, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Levothyroxine sodium, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
3,3′,5-Triiodo-L-thyronine, ≥95% (HPLC), powder,
Species
rat, human
3,3′,5-Triiodothyroacetic acid, ≥90%,
Species
rat, human
3,3′,5-Triiodo-L-thyronine sodium salt, γ-irradiated, powder, suitable for, suitable for cell culture,
Species
rat, human
3,3′,5-Triiodo-L-thyronine sodium salt, powder, BioReagent, suitable for cell culture,
Species
rat, human
L-Thyroxine, ≥98% (HPLC),
Species
human, mouse, rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-THRA antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human, mouse, pig, rat
Application
ELISA
western blot
Anti-THRA antibody produced in rabbit biotin conjugated, affinity isolated antibody,
Species Reactivity
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat, zebrafish
Application
Anti-THRA antibody produced in rabbit HRP conjugated, affinity isolated antibody,
Species Reactivity
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat, zebrafish
Application
Anti-Thyroid Hormone Receptor α, N-Terminal antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-THRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

Product Number
Description
Species
3,3′,5-Triiodo-L-thyronine, ≥95% (HPLC), powder,
Species
rat, human
3,3′,5-Triiodo-L-thyronine sodium salt, γ-irradiated, powder, suitable for, suitable for cell culture,
Species
rat, human
3,3′,5-Triiodo-L-thyronine sodium salt, powder, BioReagent, suitable for cell culture,
Species
rat, human

Proteins

Product Number
Description
Species
TR, α1, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Species
human
Thyroid Hormone receptor,α1 human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Thra,
Species
mouse
MISSION® esiRNA, targeting human THRA,
Species
human