TRAF3
TNF receptor-associated factor 3
Synonyms:
CAP-1, CAP1, CD40bp, CRAF1, IIAE5, LAP1
Species:
Human TRAF3 (7187), Mouse Traf3 (22031), Rat Traf3 (362788), cow TRAF3 (506182), dog TRAF3 (490867), chicken TRAF3 (423471), Zebrafish traf3 (445119), naked mole-rat Traf3 (101718736), domestic guinea pig Traf3 (100734492), sheep TRAF3 (100036758) ...More
UniProtKB ID:
Gene ID:
- Human(7187) Summary: The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq, Dec 2010]
- Mouse(22031) TNF receptor-associated factor 3
- Rat(362788) Tnf receptor-associated factor 3
- cow(506182) TNF receptor-associated factor 3
- dog(490867) TNF receptor-associated factor 3
- chicken(423471) TNF receptor-associated factor 3
- Zebrafish(445119) TNF receptor-associated factor 3
- naked mole-rat(101718736) TNF receptor-associated factor 3
- domestic guinea pig(100734492) TNF receptor-associated factor 3
- sheep(100036758) TNF receptor-associated factor 3
- domestic cat(101096739) TNF receptor-associated factor 3
- Horse(100055110) TNF receptor-associated factor 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-TRAF3 antibody produced in mouse, clone 1C5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
proximity ligation assay
western blot
proximity ligation assay
western blot
Anti-TRAF3 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-TRAF3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-TRAF3, from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, horse, human, mouse, rat
Application
immunohistochemistry
western blot
western blot
esiRNA
Product Number
Description
Species