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TSG101

tumor susceptibility 101

Synonyms:
TSG10, VPS23
Species:
UniProtKB ID:
Gene ID:
  • Human(7251) Summary: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]
  • Mouse(22088) tumor susceptibility gene 101
  • Rat(292925) tumor susceptibility gene 101
  • Zebrafish(415179) tumor susceptibility gene 101
  • sheep(101118061) tumor susceptibility gene 101
  • Domestic Rabbit(100343429) tumor susceptibility gene 101
  • Goat(100861362) tumor susceptibility gene 101
  • domestic guinea pig(100713139) tumor susceptibility gene 101
  • Horse(100057099) tumor susceptibility gene 101
  • fruit fly(39881) tumor suppressor protein 101
  • cow(507659) tumor susceptibility gene 101
  • naked mole-rat(101716856) tumor susceptibility gene 101
  • domestic cat(101100915) tumor susceptibility gene 101
  • dog(485406) tumor susceptibility gene 101
  • chicken(423082) tumor susceptibility gene 101

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TSG101/VPS23 Antibody, clone 4T4W6, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
Monoclonal Anti-TSG101 antibody produced in mouse, clone 5B7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-TSG101 antibody produced in mouse, ,
Species Reactivity
hamster, human, monkey, mouse, rat
Application
ELISA
flow cytometry

immunocytochemistry

immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-TSG101 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, goat, guinea pig, horse, human, mouse, rabbit, zebrafish
Application
immunohistochemistry
western blot
Rabbit anti-TSG101 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human, mouse
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TSG101,
Species
human
MISSION® esiRNA, targeting mouse Tsg101,
Species
mouse