Antibody Drug Discovery

Explore tools for therapeutic antibody discovery, from target identification to lead optimization.

HomeIntegrated OfferingsMonoclonal Antibodies (mAbs)Antibody Drug Discovery

Monoclonal antibody drug discovery begins with identifying the functional therapeutic target and evaluating its role in the disease of interest. This identification is then followed by characterization of the molecular mechanisms addressed by this target. All targets should be druggable and modulated by the potential therapeutic. These early phases have been simplified by the advent of various genome engineering and hybridoma techniques, which can be used for biotherapeutic antibody target and lead discovery.

Get ahead of the game

Uncover, select, and validate new targets with a strong link to disease. Choices made early in the drug discovery process are highly linked to ultimate failure or success in a drug discovery program. Identification of the most suitable, druggable target is key to success. We offer a complete set of curated genome-wide, pathway-specific, and protein family targeting screening tools to facilitate your target discovery.

Scientist standing and holding a box of MILLIPLEX® multiplexing biomarker assay reagents next to a Luminex® instrument with an SMCxPRO® ultrasensitive immunoassay instrument on a bench in the background
Target Discovery
  • Functional Genomics Screening Tools for Target Identification
  • In vitro Tools for Target Validation
3D illustration of antibodies in aqua and magenta
Lead Selection and Optimization
  • mAb Production
  • Purification
  • Screening and Selecting mAb Candidates
  • Lead Optimization
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Preclinical Development
  • Preclinical Models
  • PK/PD and Immunogenicity

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Related Webinars

Functional Genomics Screening

An overview of available functional genomic screening technologies, how to design successful genomics screening experiments, pooled CRISPR screening, and identification of novel drug targets.

CRISPR Tools and Technologies for Accelerating Research

An overview of genome editing possibilities, genomic exploration, identification with nuclease-deficient Cas9, and biomarker detection applications.

Future of RNAi Screening

The intersection between RNAi screening and complementary approaches such as CRISPR-Cas9-mediated genome editing has opened new opportunities for assay development, screening, and validation.

Related Categories

3D illustration of a double-stranded DNA strand in white, with a section in light pink cut out
Gene Editing & Functional Genomics

Knockout, knock-in, knockdown, or overexpress your targets with our CRISPR gene-editing tools.

An Erlenmeyer flask containing red culture media, with a serological pipet drawing up media from the flask
Cell Culture Media & Buffers

Cell culture media for cell lines, primary cells, organoids, and advanced cell models.

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Antibody Protein Purification

Chromatography purification of antibodies for lab scale, process scale, and industrial scale.

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