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15381

Sigma-Aldrich

Boc-Asn-OH

≥98.5% (T)

Synonym(s):
Boc-L-asparagine, Nα-(tert-Butoxycarbonyl)-L-asparagine
Linear Formula:
NH2COCH2CH(COOH)NHC(O)OC(CH3)3
CAS Number:
Molecular Weight:
232.23
Beilstein:
1977963
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

≥98.5% (T)

optical activity

[α]20/D −7.8±0.5°, c = 2% in DMF

reaction suitability

reaction type: Boc solid-phase peptide synthesis

application(s)

peptide synthesis: suitable

ign. residue

≤0.2%

mp

175 °C (dec.) (lit.)

SMILES string

CC(C)(C)OC(=O)N[C@@H](CC(N)=O)C(O)=O

InChI

1S/C9H16N2O5/c1-9(2,3)16-8(15)11-5(7(13)14)4-6(10)12/h5H,4H2,1-3H3,(H2,10,12)(H,11,15)(H,13,14)/t5-/m0/s1

InChI key

FYYSQDHBALBGHX-YFKPBYRVSA-N

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Storage Class Code

11 - Combustible Solids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Fei Huang et al.
Experimental cell research, 374(1), 94-103 (2018-11-21)
Hypoxia frequently occurs in solid tumors, hepatocellular carcinoma included. Hypoxia-inducible factors (HIFs) upregulated in hypoxia can induce various downstream target genes to resist hypoxia stress, resulting in tumor growth, angiogenesis and metastasis in vivo. Therefore, hypoxia associated genes are usually...
Laura D'Ignazio et al.
International journal of molecular sciences, 21(8) (2020-04-30)
NF-κB signalling is crucial for cellular responses to inflammation but is also associated with the hypoxia response. NF-κB and hypoxia inducible factor (HIF) transcription factors possess an intense molecular crosstalk. Although it is known that HIF-1α modulates NF-κB transcriptional response...
Wei Jiang et al.
Molecular immunology, 119, 8-17 (2020-01-14)
Motile sperm domain containing 2 (MOSPD2) is a single-pass membrane protein to which until recently little function had been ascribed. Although its mammalian homologs have been identified, the status of the mospd2 gene in lower vertebrates is still unknown. In...
Jan Kristoff et al.
EBioMedicine, 43, 295-306 (2019-04-07)
Despite the success of antiretroviral therapy (ART), latent HIV-1 continues to persist in a long-lived population of resting memory CD4+ T cells within those who are infected. Finding a safe and effective means to induce latency reversal (LR) during ART...
Shamroop Kumar Mallela et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1864(12), 158517-158517 (2019-09-06)
Sphingolipids have important functions as structural components of cells but they also function as signaling molecules regulating different cellular processes such as apoptosis, cell proliferation, cell migration, cell division and inflammation. Hence, a tight regulation of the sphingolipid homeostasis is...

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