155241

Sigma-Aldrich

1-Methyl-2-piperidinemethanol

98%

Synonym(s):
NSC 45464, 2-Hydroxymethyl-1-methylpiperidine
Empirical Formula (Hill Notation):
C7H15NO
CAS Number:
Molecular Weight:
129.20
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

98%

refractive index

n20/D 1.4823 (lit.)

bp

79-80 °C/7 mmHg (lit.)

density

0.984 g/mL at 25 °C (lit.)

SMILES string

CN1CCCCC1CO

InChI

1S/C7H15NO/c1-8-5-3-2-4-7(8)6-9/h7,9H,2-6H2,1H3

InChI key

HXXJMMLIEYAFOZ-UHFFFAOYSA-N

General description

The standard molar energy of combustion of 1-Methyl-2-piperidinemethanol has been studied.

Application

Reactant for synthesis of:
Selective MCH1R antagonists
Human GnRH receptor antagonists
Dual vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor 1 inhibitors
Radioiodinatable brain imaging agents for CB1 cannabinoid receptor
GABAA receptor agonists at the α3 subunit
Carbamates and N-alkylimidazoles from reaction of carbonyldiimidazoles with alcohols

Packaging

25 g in glass bottle

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

WGK Germany

WGK 3

Flash Point(F)

177.8 °F - closed cup

Flash Point(C)

81 °C - closed cup

Standard molar enthalpies of formation of 1-methyl-2-piperidinemethanol, 1-piperidineethanol, and 2-piperidineethanol.
Ribeiro da Silva, et al.
The Journal of Chemical Thermodynamics, 38(11), 1461-1466 (2006)

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