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200964

Sigma-Aldrich

Erythrosin B

Dye content ≥95 %

Synonym(s):
Solvent Red 140
Empirical Formula (Hill Notation):
C20H8I4O5
CAS Number:
Molecular Weight:
835.89
Colour Index Number:
45430:2
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

form

powder

composition

Dye content, ≥95%

application(s)

hematology: suitable
histology: suitable

mp

303 °C (dec.) (lit.)

solubility

1 M NH4OH: 1 mg/mL
spirit: soluble

λmax

533 nm

Featured Industry

Diagnostic Assay Manufacturing

storage temp.

room temp

SMILES string

Oc1c(I)cc2c(Oc3c(I)c(O)c(I)cc3C24OC(=O)c5ccccc45)c1I

InChI

1S/C20H8I4O5/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20/h1-6,25-26H

InChI key

OALHHIHQOFIMEF-UHFFFAOYSA-N

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Application

Erythrosin B has been used as a dye in fluorescence lifetime imaging.

Packaging

5, 25 g in glass bottle

Biochem/physiol Actions

Erythrosin B, also called as eosin B, is a xanthene dye. It belongs to the family of fluorescein dyes. It plays a major role in inhibiting dopamine uptake and high affinity 3H-ouabain binding and ion transport in synaptosomes from rat caudate nucleus.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Bright monomeric red fluorescent protein with an extended
fluorescence lifetime
Merzlyak EM
Nature Methods, 4, 555-557 (2007)
Practical and reliable FRET/FLIM pair of fluorescent proteins.
Shcherbo D
BMC biotechnology, 2009-2009 null
Erythrosin B is a specific inhibitor of high affinity 3H-ouabain binding and ion transport in rat brain
Silbergeld E K
Neuropharmacology, 20, 87-90 (1981)
Erythrosin B inhibits dopamine transport in rat caudate synaptosomes.
Lafferman JA and Silbergeld EK
Science, 205, :410-:412 (1979)
Hamed Gilzad Kohan et al.
Xenobiotica; the fate of foreign compounds in biological systems, 45(7), 642-652 (2015-01-08)
1. Influx and efflux proteins play a major role in the overall uptake and efficacy of chemotherapeutic agents and cellular chemo-resistance. 2. The present study investigated the time course and dose dependency of the induction of three efflux proteins, P-gp...

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