All Photos(1)

295337

Sigma-Aldrich

Trifluoromethane

≥98%

Synonym(s):
HFC-23, Fluoroform
Linear Formula:
CHF3
CAS Number:
Molecular Weight:
70.01
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

vapor density

2.43 (vs air)

vapor pressure

635 psi ( 21 °C)

assay

≥98%

bp

−84 °C (lit.)

mp

−160 °C (lit.)

SMILES string

FC(F)F

InChI

1S/CHF3/c2-1(3)4/h1H

InChI key

XPDWGBQVDMORPB-UHFFFAOYSA-N

Packaging

227 g in steel cylinder

Recommended products

Z146706 CGA 180 Regulator OR Z146943 CGA 110 Valve, with Z147095 CGA 110 to CGA 180 adapter and Z146986 washer for valve. Also recommended Z562599 CGA 180 Lecture-Bottle station.

Pictograms

Gas cylinder

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Press. Gas Liquefied gas

Storage Class Code

2A - Gases

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Naleen B Jayaratna et al.
Inorganic chemistry, 52(4), 1691-1693 (2013-02-02)
Silver and copper ethylene adducts and the silver carbonyl complex of the tris(pyrazolyl)borate [HB(3,4,5-(CF(3))(3)Pz)(3)](-) (which is based on one of the most acidic pyrazoles known) have been synthesized. (13)C NMR resonance signals of metal-bound ethylene carbon atoms of [HB(3,4,5-(CF(3))(3)Pz)(3)]Ag(C(2)H(4)) and...
Alessandro Zanardi et al.
Journal of the American Chemical Society, 133(51), 20901-20913 (2011-12-06)
We have found the first reaction of direct cupration of fluoroform, the most attractive CF(3) source for the introduction of the trifluoromethyl group into organic molecules. Treatment of CuX (X = Cl, Br, I) with 2 equiv of MOR (M...
Charles S Thomoson et al.
The Journal of organic chemistry, 78(17), 8904-8908 (2013-08-13)
Fluoroform, CHF3, a non-ozone-depleting, nontoxic, and inexpensive gas can be used as a difluorocarbene source in a process for the conversion of phenols and thiophenols to their difluoromethoxy and difluorothiomethoxy derivatives. The reactions are carried out at moderate temperatures and...
Mark A Honey et al.
The Journal of organic chemistry, 77(3), 1396-1405 (2012-01-24)
Ethyl 2-diazo-4,4,4-trifluoro-3-oxobutanoate is a highly versatile intermediate for the synthesis of a wide range of trifluoromethyl heterocycles. With the use of rhodium(II) or copper(II) catalyzed carbene X-H insertion reactions as key steps, a diverse set of trifluoromethyl-oxazoles, -thiazoles, -imidazoles, -1,2,4-triazines...
Shun Noritake et al.
Organic & biomolecular chemistry, 7(17), 3599-3604 (2009-08-14)
Chiral nonracemic guanidines act as Brønsted bases to generate guanidinium enolates for the enantioselective electrophilic trifluoromethylation of beta-keto esters by means of S-(trifluoromethyl)dibenzothiophenium tetrafluoroborate (Umemoto reagent) with good enantioselectivity of 60-70% range. Despite the fact that the ees are still...

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