γ-Ethyl-γ-butyrolactone, gamma-Caprolactone
Empirical Formula (Hill Notation):
CAS Number:
Molecular Weight:
Beilstein/REAXYS Number:
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PubChem Substance ID:
Pricing and availability is not currently available.

Quality Level



refractive index

n20/D 1.439 (lit.)


219 °C (lit.)


1.023 g/mL at 25 °C (lit.)

SMILES string




InChI key


Gene Information

human ... CYP1A2(1544)

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General description

γ-caprolactone (GCL) is well-known as a food flavor and is a biostimulant molecule promoting the growth of bacteria with biocontrol activity against soft-rot pathogens. GCL treatment stimulates growth of the native quorum sensing-degrading bacterial community in an industrial plant hydroponic system for culturing Solanum tuberosum.


γ-Caprolactone was used as curing agent for diglycidyl ether of bisphenol A with ytterbium triflate as an initiator.


25 g in glass bottle

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 303836.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.


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Hazard Statements

Precautionary Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes


Risk Statement


Safety Statement



NONH for all modes of transport

WGK Germany


Flash Point(F)

208.4 °F - closed cup

Flash Point(C)

98 °C - closed cup

Amélie Cirou et al.
Research in microbiology, 162(9), 945-950 (2011-02-04)
Bacteria degrading quorum sensing (QS) signals have been proposed as biocontrol agents able to quench QS-dependent expression of virulence symptoms caused by Pectobacterium on potato plants. We report here that gamma-caprolactone (GCL) treatment stimulated growth of the native QS-degrading bacterial...
Corinne Barbey et al.
Journal of proteome research, 11(1), 206-216 (2011-11-17)
Gamma-caprolactone (GCL) is well-known as a food flavor and has been recently described as a biostimulant molecule promoting the growth of bacteria with biocontrol activity against soft-rot pathogens. Among these biocontrol agents, Rhodococcus erythropolis, characterized by a remarkable metabolic versatility...
New thermosets obtained by the cationic copolymerization of diglycidyl ether of bisphenol A with ?-caprolactone with an improvement in the shrinkage. I. Study of the chemical processes and physical characteristics.
Gonzalez S, et al.
Journal of Polymer Science Part A: Polymer Chemistry, 45(10), 1968-1979 (2007)
Olga Khersonsky et al.
Biochemistry, 44(16), 6371-6382 (2005-04-20)
PON1 is the best-studied member of a family of enzymes called serum paraoxonases, or PONs, identified in mammals (including humans) and other vertebrates as well as in invertebrates. PONs exhibit a range of important activities, including drug metabolism and detoxification...
Cindy Chung et al.
Biomaterials, 30(26), 4287-4296 (2009-05-26)
The potential of mesenchymal stem cells (MSCs) as a viable cell source for cartilage repair hinges on the development of engineered scaffolds that support adequate cartilage tissue formation. Evolving networks (hydrogels with mesh sizes that change over time due to...

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