344729

Sigma-Aldrich

1-Acetyl-3-methylpiperidine

99%

Synonym(s):
1-(3-Methyl-1-piperidinyl)-ethanone, 1-Acetyl-3-pipecoline
Empirical Formula (Hill Notation):
C8H15NO
CAS Number:
Molecular Weight:
141.21
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

assay

99%

refractive index

n20/D 1.476 (lit.)

bp

239 °C (lit.)

mp

−15 °C (lit.)

density

0.974 g/mL at 25 °C (lit.)

SMILES string

CC1CCCN(C1)C(C)=O

InChI

1S/C8H15NO/c1-7-4-3-5-9(6-7)8(2)10/h7H,3-6H2,1-2H3

InChI key

XKFPNHDGLSYZRC-UHFFFAOYSA-N

Application

1-Acetyl-3-methylpiperidine may be employed as piperidine ligand to investigate the enzymatic activity and three-dimensional structure non-peptide ligand-cyclophilin complexes.
Reactant for:
Regioselective amidyl radical cyclization
Regioselective oxidation of cyclic amino compounds

Packaging

25 g in glass bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

224.6 °F - closed cup

Flash Point(C)

107 °C - closed cup

George Kontopidis et al.
Acta crystallographica. Section D, Biological crystallography, 60(Pt 3), 479-485 (2004-03-03)
Piperidine ligands are described that provide the first examples of non-peptidic ligand structures for the cyclophilin family of proteins. Crystal structures of two ligand complexes are compared with the unliganded protein and show ligand-induced changes in side-chain conformation and water...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.