Fereidoon Daryaee et al.
European journal of medicinal chemistry, 44(1), 289-295 (2008-04-26)
On the basis of the structural similarity of N-substituted glycolamides with N-glycolyl muramic acid residues of the cell wall of Mycobacterium tuberculosis, a series of these compounds were designed and synthesized by the reaction of glycolic acid acetonide 1 (2,2-dimethyl-5-oxo-1,3-dioxolane)...
Parmeshwari K Halen et al.
Mini reviews in medicinal chemistry, 9(1), 124-139 (2009-01-20)
Non-steroidal anti-inflammatory drugs (NSAIDs), commonly used for the treatment of chronic inflammatory diseases suffer from several undesired side effects, the most important being gastrointestinal (GI) irritation and ulceration. The prodrug designing is one of the several strategies used to overcome...
Partial molal isothermal compressibility of glycine, DL-α-alanine, glycylglycine, glycolamide, and lactamide.
The Journal of Physical Chemistry, 97(49), 13027-13028 (1993)
A K Bansal et al.
Drug development and industrial pharmacy, 27(1), 63-70 (2001-03-15)
Glycolamide esters of ibuprofen (I), namely, unsubstituted (II), N,N dimethyl (III), and N,N diethyl (IV), were synthesized and studied for different physicochemical, pharmacological, and toxicological properties. They were comparable with I in respect of anti-inflammatory and analgesic activity but did...
P R Brown et al.
Journal of general microbiology, 133(6), 1527-1533 (1987-06-01)
A positive selection is described for isolating amidase-negative mutants from Pseudomonas aeruginosa strains. The method is based on the conversion, via amidase activity, of glycollamide to glycollate which is growth inhibitory. Three types of mutant were isolated on lactate medium...