512338

Sigma-Aldrich

4-(Hydroxymethyl)phenylboronic acid

≥95%

Synonym(s):
4-Hydroxymethylbenzeneboronic acid, α-Hydroxy-p-tolueneboronic acid
Linear Formula:
HOCH2C6H4B(OH)2
CAS Number:
Molecular Weight:
151.96
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

≥95%

mp

251-256 °C (lit.)

SMILES string

OCc1ccc(cc1)B(O)O

InChI

1S/C7H9BO3/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4,9-11H,5H2

InChI key

PZRPBPMLSSNFOM-UHFFFAOYSA-N

Application

Reactant involved in the synthesis of biologically active compounds including:
  • Imidazo[4,5-b]pyrazin-2-ones for use as mTOR kinase inhibitors
  • Human immunodificiency virus protease inhibitors with activity against resistant viruses

Reactant involved in:
  • Suzuki coupling reactions
  • Copper-catalyzed transformation from arylboronic acids in water

Involved in the synthesis of polyurethane containing spindle-type chromophores

Packaging

1, 10 g in glass bottle

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Tetrahedron Asymmetry, 14, 3435-3446 (2003)

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