The influence of aromatic compound protonation on the regioselectivity of Gattermann-Koch formylation.
Tanaka M, et al.
Chemical Communications (Cambridge, England), 2, 159-160 (1996)
S Amin et al.
Chemical research in toxicology, 1(6), 349-355 (1988-11-01)
Previous studies have shown that 5-methylchrysene (5-MeC) is more carcinogenic on mouse skin than the other methylchrysenes and that the structural requirements favoring tumorigenicity of methylated polynuclear aromatic hydrocarbons are the presence of a bay region methyl group and free...
Stéphanie Kolb et al.
European journal of medicinal chemistry, 45(3), 896-901 (2009-12-09)
We report herein the synthesis of 5-substituted pyrindine derivatives and the evaluation of their antiproliferative properties on HeLa cells, a cervical carcinoma tumor cell line, and on the melanoma A2058 cell line. The most efficient compounds display cytotoxicity against tumor...