903027

QPhos Pd G3

• Synonym(s): QPhos G3 Palladacycle, QPhos Palladacycle
• Empirical Formula (Hill Notation): C₆₁H₆₀FeNO₃PPdS
• CAS Number: 2021255-91-2
• Molecular Weight: 1080.44
• MDL number: MFCD12911997

Properties

• form: powder
• feature: generation 3
• reaction suitability: core: palladium; reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: catalyst; reaction type: Cross Couplings
• functional group: phosphine

Description

General description

QPhos Pd G3 is a third generation (G3) Buchwald precatalyst. It is air, moisture and thermally-stable and is highly soluble in a wide range of common organic solvents. It has long life in solutions. Qphos Pd G3 is an excellent reagent for palladium catalyzed cross-coupling reactions. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.

Application

QPhos Pd G3 has been used as a precatalyst for the arylboration of isoprene with regioselectivity. It may also be used for a variety of aminination and etherifications of aryl halides.

Other Notes

Technology Spotlight: G3 and G4 Buchwald Precatalysts

Regioselective Arylboration of Isoprene and Its Derivatives by Pd/Cu Cooperative Catalysis

Synthesis of Complex Drug like Molecules by the Use of Highly Functionalized Bench-Stable Organozinc Reagents

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable