D7148

3,4-Diaminopyridine

≥98%

• Empirical Formula (Hill Notation): C₅H₇N₃
• CAS Number: 54-96-6
• Molecular Weight: 109.13
• Beilstein: 110232
• EC Number: 200-220-9
• MDL number: MFCD00006401
• PubChem Substance ID: 57654120
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: ≥98%
• form: powder
• mp: 216-218 °C (lit.)
• SMILES string: Nc1ccncc1N
• InChI: 1S/C5H7N3/c6-4-1-2-8-3-5(4)7/h1-3H,7H2,(H2,6,8)
• InChI key: OYTKINVCDFNREN-UHFFFAOYSA-N
• Gene Information: human ... KCNA1(3736) , KCNA10(3744) , KCNA2(3737) , KCNA3(3738) , KCNA4(3739) , KCNA5(3741) , KCNA6(3742) , KCNA7(3743) , KCNB1(3745) , KCNB2(9312) , KCNC1(3746) , KCNC2(3747) , KCNC3(3748) , KCNC4(3749) , KCND1(3750) , KCND2(3751) , KCND3(3752) , KCNF1(3754) , KCNG1(3755) , KCNG2(26251) , KCNG3(170850) , KCNG4(93107) , KCNH1(3756) , KCNH2(3757) , KCNH3(23416) , KCNH4(23415) , KCNH5(27133) , KCNH6(81033) , KCNH7(90134) , KCNH8(131096) , KCNQ1(3784) , KCNQ2(3785) , KCNQ3(3786) , KCNQ4(9132) , KCNQ5(56479) , KCNS1(3787) , KCNS2(3788) , KCNS3(3790) , KCNV1(27012) , KCNV2(169522)

Description

Application

3,4-Diaminopyridine can be used as a heterocyclic building block to prepare:      

• Imidazo[4,5-c]pyridine, an important scaffold used for the preparation of CP-885316.     
• 9-Azajulolidine derivatives, which are used as efficient organocatalysts for acylation and aza-Morita-Baylis-Hillman reaction.      
• 2-Phenylpyrido[3,4-b]pyrazine by condensation reaction with α-methylsulfinylacetophenone in benzene/acetic acid as a solvent.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H300 + H330 - H311 - H319
• Precautionary Statements: P260 - P264 - P280 - P302 + P352 + P312 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Eye Irrit. 2
• Storage Class Code: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves