H49804

Sigma-Aldrich

2-Hydroxyphenylacetic acid

ReagentPlus®, 99%

Linear Formula:
HOC6H4CH2CO2H
CAS Number:
Molecular Weight:
152.15
Beilstein/REAXYS Number:
908000
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

product line

ReagentPlus®

Quality Level

assay

99%

mp

145-147 °C (lit.)

SMILES string

OC(=O)Cc1ccccc1O

InChI

1S/C8H8O3/c9-7-4-2-1-3-6(7)5-8(10)11/h1-4,9H,5H2,(H,10,11)

InChI key

CCVYRRGZDBSHFU-UHFFFAOYSA-N

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Related Categories

Packaging

10, 25 g in poly bottle

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. H49804.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

S L Born et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 41(2), 247-258 (2002-12-14)
Coumarin, a well recognized rat hepatotoxicant, also causes acute, selective necrosis of terminal bronchiolar Clara cells in the mouse lung. Further, chronic oral gavage administration of coumarin at 200 mg/kg, a dose that causes Clara cell death, resulted in a...
D Ratanasavanh et al.
Fundamental & clinical pharmacology, 10(6), 504-510 (1996-01-01)
We compared the cytotoxic effect of coumarin and its derivatives, 7-hydroxycoumarin (7-OHC), 4-hydroxycoumarin (4-OHC), o-hydroxyphenyl acetic acid (OHPAA) and o-coumaric acid (CA), on cultured hepatocytes from human, rat, mouse and rabbit liver. At 10(-5) and 5 x 10(-5) M, coumarin...
M Bayat-Sarmadi et al.
Molecular and cellular endocrinology, 92(1), 127-134 (1993-03-01)
Prolactin has many known functions and one of them is to induce the expression of milk protein gene expression in the mammary gland. Specific membrane receptors have been recently characterized but the transduction mechanism involved in the transfer of the...
Jeffrey D Vassallo et al.
Toxicological sciences : an official journal of the Society of Toxicology, 80(2), 249-257 (2004-05-14)
Hepatotoxicity of coumarin is attributed to metabolic activation to an epoxide intermediate, coumarin 3,4-epoxide (CE). However, whereas rats are most susceptible to coumarin-induced hepatotoxicity, formation of CE is greatest in mouse liver microsomes, a species showing little evidence of hepatotoxicity....
Noureddine Allouche et al.
Journal of agricultural and food chemistry, 53(16), 6525-6530 (2005-08-04)
We investigated to develop an effective procedure to produce the potentially high-added-value phenolic compounds through bioconversion of tyrosol isomers. A soil bacterium, designated Serratia marcescens strain, was isolated on the basis of its ability to grow on p-tyrosol (4-hydroxyphenylethanol) as...

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