R M Hanif et al.
Chemical & pharmaceutical bulletin, 46(9), 1428-1431 (1998-10-17)
The tetrahydrogeraniol (THG) derivative, ethyl-(3,7-dimethyl octyl thio) acetate (EDOTA) was prepared by reacting tetrahydrogeranyl bromide (obtained by reaction of 40% hydrobromic acid and concentrated sulfuric acid) with ethyl 2-mercaptoacetate, while 3,7-dimethyl octyl propionate (DOP) was synthesized by a common esterification...
J Pevsner et al.
The Journal of biological chemistry, 265(11), 6118-6125 (1990-04-15)
We have characterized the odorant binding properties of purified bovine odorant-binding protein (OBP) using as a ligand [3H]3,7-dimethyloctan-1-ol ([3H]DMO). A broad variety of odorants, including terpenes, aldehydes, esters, and musks, bind to OBP with affinities of 0.2 to 100 microM....
Gul Majid Khan et al.
Pakistan journal of pharmaceutical sciences, 24(4), 451-457 (2011-10-01)
In the present study a new alcohol derivative of tetrahydrogeraniol (THG), an acyclic monoterpene, has been prepared by using Grignard reagent and methyl cyclopropyl ketone. Penetration enhancing effects of THG and the synthesized derivative 5,9-dimethyl-2-cyclopropyl-2-decanol (DICNOL) on the transdermal penetration...
A Lapczynski et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 46 Suppl 11, S139-S141 (2008-07-22)
A toxicologic and dermatologic review of 3,7-dimethyl-1-octanol when used as a fragrance ingredient is presented.
R M Hanif et al.
Journal of controlled release : official journal of the Controlled Release Society, 55(2-3), 297-302 (1998-10-31)
Poly(acrylic acid) gels containing 5-fluorouracil (5-FU) and tetrahydrogeraniol (THG) were prepared and the effects of THG on 5-FU permeation across the excised rat skin were studied by in vitro methods. Experiments on in vitro permeation of 5-FU across the skin...