All Photos(1)

W325201

Sigma-Aldrich

β-Alanine

≥98%, FG

Synonym(s):
3-Aminopropionic acid, β-Ala
Linear Formula:
NH2CH2CH2COOH
CAS Number:
Molecular Weight:
89.09
FEMA Number:
3252
Beilstein:
906793
EC Number:
MDL number:
PubChem Substance ID:
Flavis number:
17.001
NACRES:
NA.21

Quality Level

biological source

synthetic

grade

FG
Halal

reg. compliance

EU Regulation 1334/2008 & 872/2012

assay

≥98%

mp

202 °C (dec.) (lit.)

Documentation

see Safety & Documentation for available documents

Organoleptic

odorless

application(s)

flavors and fragrances

food allergen

no known allergens

SMILES string

NCCC(O)=O

InChI

1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)

InChI key

UCMIRNVEIXFBKS-UHFFFAOYSA-N

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Packaging

5, 10 kg in fiber drum
1 kg in poly bottle

Biochem/physiol Actions

β-Alanine, a β−amino acid, is a component of pantothenic acid and the rate-limiting amino acid in the biosynthesis of the histidinyl antioxidant dipeptides carnosine and anserine. Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine flux plays a cytoprotective role by supporting the osmotic stability of marine organisms, preimplantation mouse embryos and mammalian cells exposed to hypoxic stress.
Ramin Artang et al.
The American journal of cardiology, 112(12), 1973-1979 (2013-10-01)
Dabigatran has been associated with greater risk of myocardial infarction (MI) than warfarin. It is unknown whether the increased risk is unique to dabigatran, an adverse effect shared by other oral direct thrombin inhibitors (DTIs), or the result of a
Robert G Hart et al.
The Canadian journal of cardiology, 29(7 Suppl), S71-S78 (2013-06-29)
Chronic kidney disease (CKD) is prevalent in elderly patients with atrial fibrillation and is an independent risk factor for stroke. Warfarin anticoagulation is efficacious for stroke prevention in atrial fibrillation patients with moderate CKD (stage III, estimated glomerular filtration rate
Ammar Majeed et al.
Circulation, 128(21), 2325-2332 (2013-10-02)
The aim of this study was to compare the management and prognosis of major bleeding in patients treated with dabigatran or warfarin. Two independent investigators reviewed bleeding reports from 1034 individuals with 1121 major bleeds enrolled in 5 phase III
Wilma Potze et al.
British journal of haematology, 163(5), 666-673 (2013-11-14)
There is increasing recognition that thrombotic complications may occur in patients with cirrhosis, and literature on antithrombotic treatment in these patients is rapidly emerging. Due to extensive haemostatic changes in patients with cirrhosis, careful monitoring of anticoagulant therapy may be
K M Gibson et al.
Journal of neurochemistry, 81(1), 71-79 (2002-06-18)
Metabolite profiling in succinate semialdehyde dehydrogenase (SSADH; Aldh5a1-/-) deficient mice previously revealed elevated gamma-hydroxybutyrate (GHB) and total GABA in urine and total brain and liver extracts. In this study, we extend our metabolic characterization of these mutant mice by documenting

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