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W502707

Sigma-Aldrich

Succinic acid

FCC

Synonym(s):
Butanedioic acid
Linear Formula:
HOOCCH2CH2COOH
CAS Number:
Molecular Weight:
118.09
FEMA Number:
4719
Beilstein:
1754069
EC Number:
Council of Europe no.:
24
MDL number:
PubChem Substance ID:
Flavis number:
8.024

biological source

synthetic

grade

Halal
Kosher

reg. compliance

FCC
FDA 21 CFR 184.1091

assay

99.0-100.5% (by NaOH, titration)

form

crystals

bp

235 °C (lit.)

mp

184-186 °C (lit.)

solubility

water: soluble 83 g/L at 25 °C

density

1.564 g/cm3 at 15 °C

cation traces

As: ≤3 ppm
Cd: ≤1 ppm
Hg: ≤1 ppm
Pb: ≤2 ppm

Documentation

see Safety & Documentation for available documents

Organoleptic

acidic; sour

application(s)

flavors and fragrances

food allergen

no known allergens

SMILES string

OC(=O)CCC(O)=O

InChI

1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

InChI key

KDYFGRWQOYBRFD-UHFFFAOYSA-N

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James H Marden et al.
Evolution; international journal of organic evolution, 67(4), 1105-1115 (2013-04-05)
Oxygen conductance to the tissues determines aerobic metabolic performance in most eukaryotes but has cost/benefit tradeoffs. Here we examine in lowland populations of a butterfly a genetic polymorphism affecting oxygen conductance via the hypoxia-inducible factor (HIF) pathway, which senses intracellular
José Manuel Otero et al.
PloS one, 8(1), e54144-e54144 (2013-01-26)
Saccharomyces cerevisiae is the most well characterized eukaryote, the preferred microbial cell factory for the largest industrial biotechnology product (bioethanol), and a robust commerically compatible scaffold to be exploitted for diverse chemical production. Succinic acid is a highly sought after
G M Tannahill et al.
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Macrophages activated by the Gram-negative bacterial product lipopolysaccharide switch their core metabolism from oxidative phosphorylation to glycolysis. Here we show that inhibition of glycolysis with 2-deoxyglucose suppresses lipopolysaccharide-induced interleukin-1β but not tumour-necrosis factor-α in mouse macrophages. A comprehensive metabolic map
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Current opinion in biotechnology, 24(6), 965-972 (2013-04-02)
Bio-based production of chemical building blocks from renewable resources is an attractive alternative to petroleum-based platform chemicals. Metabolic pathway and strain engineering is the key element in constructing robust microbial chemical factories within the constraints of cost effective production. Here

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