01542

Supelco

Chrysophanol

analytical standard

Synonym(s):
Chrysophanic acid, 3-Methylchrysazin, 1,8-Dihydroxy-3-methylanthraquinone
Empirical Formula (Hill Notation):
C15H10O4
CAS Number:
Molecular Weight:
254.24
Beilstein/REAXYS Number:
1252300
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24
Pricing and availability is not currently available.

Quality Level

grade

analytical standard

assay

≥98.0% (HPLC)

CofA

certificate is enclosed in each package

shelf life

limited shelf life, expiry date on the label

application(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

192-196 °C

suitability

conforms to structure for Proton NMR spectrum

Featured Industry

Food and Beverages

format

neat

storage temp.

2-8°C

SMILES string

Cc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1

InChI

1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3

InChI key

LQGUBLBATBMXHT-UHFFFAOYSA-N

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General description

Chrysophanol is an anthraquinone compound and occurs naturally in Chinese herb Rheum officinale. It shows antimicrobial activity, and is an active component in many crude drugs having purgative properties.

Application

It may be used as reference standard in analyzing bioactive components (hyperin, nobiletin, hesperidin, emodin, chrysophanol, resveratrol, curcumine, and physcion) in Danning tablets using HPLC-UV and HPLC-ESI-MS.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Codes

Xi

Risk Statement

36/38

Safety Statement

26

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Chrysophanol, an antimicrobial anthraquinone from the root extract of Colubrina greggii.
Garcia-Sosa, Karlina, et al.
Journal of the Mexican Chemical Society, 50.2, 76-78 (2006)
Myung Sun Lee et al.
Phytotherapy research : PTR, 25(6), 833-837 (2010-11-23)
Inactivation of epidermal growth factor receptor (EGFR) is a prime method used in colon cancer therapy. Here it is shown that chrysophanic acid, a natural anthraquinone, has anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells. Chrysophanic acid preferentially blocked...
Simultaneous analysis of eight bioactive compounds in Danning tablet by HPLC-ESI-MS and HPLC-UV.
Liu R
Journal of Pharmaceutical and Biomedical Analysis, 43(3), 1007-1012 (2007)
Anne C Jones et al.
Die Naturwissenschaften, 99(7), 583-586 (2012-06-23)
The nonnative hemlock woolly adelgid (Adelges tsugae Annand, Hemiptera: Sternorrhyncha: Adelgidae) has been a significant mortality agent of eastern hemlock (Tsuga canadensis Carriere) throughout a large portion of its geographic range. During a study investigating adelgid vigor in relation to...
Tiffany Chien-Ting Lo et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 893-894, 101-106 (2012-03-23)
Chrysophanol has high pharmaceutical values. However, it was difficult to use the traditional extraction method to extract high-concentration chrysophanol. Therefore, the purpose of this study is to purify and separate chrysophanol in traditional herb, Rheum Palmatum LINN, by using supercritical...

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