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2,3,4,5,6-Pentafluorobenzoic anhydride

for GC derivatization, ≥98.0%

Empirical Formula (Hill Notation):
CAS Number:
Molecular Weight:
MDL number:
PubChem Substance ID:

Quality Level


for GC derivatization


≥98.0% (GC)

reaction suitability

reagent type: derivatization reagent
reaction type: Acylations


66-70 °C

SMILES string




InChI key


Other Notes

Derivatizing reagent for lipids

Certificate of Analysis

Certificate of Origin

S T Weintraub et al.
Journal of the American Society for Mass Spectrometry, 11(2), 176-181 (2000-02-26)
Platelet-activating factor is the term used to denote a class of extremely potent lipid mediators that consist predominantly of 1-O-alkyl- and 1-O-acyl-2-acetyl-sn-glycero-3-phosphocholines. A method has been devised for rapid isolation of these acetylated phospholipids by solid-phase extraction prior to direct
D V Crabtree et al.
Journal of chromatography, 466, 251-270 (1989-04-19)
Pentafluorobenzoate derivatives of primary and secondary alcohols have been prepared using pentafluorobenzoic anhydride. The gas chromatographic properties of the homologous series of the methyl esters of 2-hydroxycarboxylic acids from C12 to C26 have been studied on the high-temperature stationary phase
D S Woodard et al.
Biochimica et biophysica acta, 1259(2), 137-147 (1995-11-16)
Platelet-activating factor (PAF), a family of phospholipid autacoids with potent pro-inflammatory activities, is present in saliva. The current study has quantitated various species of PAF isolated from normal human mixed saliva. Choline-containing, sn-2 acetylated phospholipids with sn-1 ether- or ester-linked
Synthesis of pentafluorobenzoic anhydride: a superior derivatizing agent for lipids.
S T Weintraub et al.
Analytical chemistry, 65(17), 2400-2402 (1993-09-01)
B H Chen et al.
Journal of analytical toxicology, 14(1), 12-17 (1990-01-01)
Pentafluoropropionic anhydride (PFPA) and heptafluorobutyric anhydride (HFBA) derivatives of morphine and codeine demonstrated poor spectra due to low abundances of secondary and tertiary ions. Trifluoroacetamide (MBTFA) has been a widely used derivative; however, the internal standard, nalorphine, displayed very poor

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