Sodium Butyrate Induces NIH3T3 cells to senescence-like state and enhances promoter activity of p21WAF/CIP1in p53-Independent manner.
Xiao H, et al.
Biochemical and Biophysical Research Communications, 237(2), 457-460 (1997)
Fight Cancer with Vitamins and Supplements: A Guide to Prevention and Treatment (2001)
Jing Jiang et al.
Scientific reports, 5, 9191-9191 (2015-03-18)
Epithelial barrier integrity is critical to maintain the homeostasis in the body. The regulatory mechanism of the epithelial barrier function has not been fully understood. This study aims to elucidate the role of the TWIK-related potassium channel-1 (Trek1) in the...
Youngmi Cho et al.
Experimental biology and medicine (Maywood, N.J.), 239(3), 302-310 (2014-02-06)
DNA methylation and histone acetylation contribute to the transcriptional regulation of genes involved in apoptosis. We have demonstrated that docosahexaenoic acid (DHA, 22:6 n-3) and butyrate enhance colonocyte apoptosis. To determine if DHA and/or butyrate elevate apoptosis through epigenetic mechanisms thereby...
Regina Kanski et al.
Journal of cell science, 127(Pt 20), 4368-4380 (2014-08-17)
Glial fibrillary acidic protein (GFAP) is the main intermediate filament in astrocytes and is regulated by epigenetic mechanisms during development. We demonstrate that histone acetylation also controls GFAP expression in mature astrocytes. Inhibition of histone deacetylases (HDACs) with trichostatin A...