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12070

Sigma-Aldrich

Benzamide

purum, ≥98.0% (HPLC)

Synonym(s):
Benzoic acid amide
Linear Formula:
C6H5CONH2
CAS Number:
Molecular Weight:
121.14
Beilstein:
385876
EC Number:
MDL number:
PubChem Substance ID:

grade

purum

assay

≥98.0% (HPLC)

mp

125-128 °C (lit.)
125-128 °C

solubility

methanol: soluble 1 g/10 mL, clear, colorless to faintly yellow

SMILES string

NC(=O)c1ccccc1

InChI

1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9)

InChI key

KXDAEFPNCMNJSK-UHFFFAOYSA-N

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Application

Benzamide was used to study the effect of inhibitors of endonuclease and poly(ADP ribose) polymerase on anti-Fas monoclonal antibody treated Jurkat cells.

Biochem/physiol Actions

Benzamide is a specific inhibitor of poly(ADP-ribose)polymerase. It prevents glutamate- and methamphetamine-induced neurotoxicity in vitro in C57B1/6N mouse.
Inhibits poly(ADP-ribose) polymerase (PARP).

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Certificate of Origin

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