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16499

Supelco

Ipriflavone

analytical standard

Synonym(s):
7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one, Ipriflavone
Empirical Formula (Hill Notation):
C18H16O3
CAS Number:
Molecular Weight:
280.32
MDL number:
PubChem Substance ID:

grade

analytical standard

Quality Level

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

application(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

116-120 °C (lit.)

format

neat

SMILES string

CC(C)Oc1ccc2c(OC=C(C2=O)c3ccccc3)c1

InChI

1S/C18H16O3/c1-12(2)21-14-8-9-15-17(10-14)20-11-16(18(15)19)13-6-4-3-5-7-13/h3-12H,1-2H3

InChI key

SFBODOKJTYAUCM-UHFFFAOYSA-N

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General description

Ipriflavone, a flavonoid derivative of the natural isoflavone compound, plays a role in the mitochondrial phosphorylation and exhibits growth-promoting activity.

Application

Ipriflavone can be used as an analytical standard for the determination of the analyte in human and animal biological samples by liquid chromatography (LC) based methods.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Simultaneous determination of ipriflavone and its main metabolites M1 and M5 in human plasma by liquid chromatography with tandem mass spectrometry
Ji HY, et al.
Analytical Letters, 38(1), 99-110 (2005)
Determination of ipriflavone and its synthetic impurities by high-performance liquid chromatography using diode-array detection
Sustacha K, et al.
Journal of Chromatography A, 719(1), 245-250 (1996)
Disposition of ipriflavone (TC-80) in rats and dogs.
Yoshida K, et al.
Radioisotopes, 34(11), 618-623 (1985)
Pharmacokinetics of ipriflavone, an isoflavone derivative, after intravenous and oral administration to rats: hepatic and intestinal first-pass effects
Kim SH and Lee MG
Life Sciences, 70(11), 1299-1315 (2002)
Hye J Chung et al.
The Journal of pharmacy and pharmacology, 58(4), 449-457 (2006-04-07)
In order to find out what types of the hepatic microsomal cytochrome P450 (CYP) isozymes are involved in the metabolism of ipriflavone, ipriflavone at a dose of 20 mg kg(-1) (or 15 mg kg(-1)) was infused in male Sprague-Dawley rats....

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