21223

Sigma-Aldrich

Hydroxyapatite

purum p.a., ≥90% (as Ca3(PO4)2, KT)

Synonym(s):
Durapatite, Hydroxylapatite, Calcium phosphate hydroxide
Linear Formula:
3Ca3(PO4)2 · Ca(OH)2
CAS Number:
Molecular Weight:
502.31
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21
Pricing and availability is not currently available.

Quality Level

grade

purum p.a.

assay

≥90% (as Ca3(PO4)2, KT)

form

powder

impurities

≤5% water (KFT)

loss

≤10% loss on ignition, 800 °C

anion traces

chloride (Cl-): ≤500 mg/kg
sulfate (SO42-): ≤2000 mg/kg

cation traces

Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cu: ≤20 mg/kg
Fe: ≤400 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤10 mg/kg

SMILES string

Ca++.Ca++.Ca++.Ca++.OCa+.O-P(O-)(O-)=O.O-P(O-)(O-)=O.O-P(O-)(O-)=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

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General description

Bone and tooth implant materials have been prepared from polycrystalline hydroxyapatite. The compressive, flexural, torsional and dynamic torsional strengths of polycrystalline hydroxyapatite were investigated. Electrophoretic deposition of hydroxyapatite on to flat titanium plate material has been studied.
Hydroxyapatite is a bioceramic mainly found in minerals of bone and teeth. Due to its high biocompatibility and similarity with inorganic components found in hard tissues, it is mainly used to produce biocomposites and prostheses for bones and teeth replacement.

Application

Hydroxyapatite may be used in the preparation of bioceramic specimens by incorporation of a small amount of silicon (0.4wt%) into the structure of hydroxyapatite. It may be used for the preparation of porous microstructures, having important prosthetic applications.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

Xi

Risk Statement

36/37/38

Safety Statement

26

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Hydroxyapatite synthesis and the benefits of its blend with calcium aluminate cement.
Oliveira IR, et al.
Ceramics International, 42(2), 2542-2549 (2016)
Chemical characterization of silicon-substituted hydroxyapatite
Gibson I, et al.
Journal of Biomedical Materials Research, 44(4), 422-428 (1999)
P Ducheyne et al.
Biomaterials, 7(2), 97-103 (1986-03-01)
Hydroxyapatite from two sources was electrophoretically deposited onto flat titanium plate material. Depending upon the deposition conditions various changes in the structure of the ceramic were identified. A well-adhering Ti-P compound was present at the interface. Hydroxyapatite oxygenated to various...
Mechanical properties of sintered hydroxyapatite for prosthetic applications.
Akao M ,et al.
J. Mater. Sci., 16(3), 809-812 (1981)
H S Alghamdi et al.
Journal of dental research, 92(11), 982-988 (2013-09-24)
Osteoporotic conditions are anticipated to affect the osseointegration of dental implants. This study aimed to evaluate the effect of a radiofrequent magnetron-sputtered calcium phosphate (CaP) coating on dental implant integration upon installment in the femoral condyles of both healthy and...

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